IL16 Antikörper (N-Term)

Produktnummer ABIN6991050

Dieser Anti-IL16 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von IL16 in WB, ELISA, IF und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für IL16 Antikörper (N-Term) (ABIN6991050)

Target: IL16 (Interleukin 16 (IL16))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IL16 Antikörper

Bindungsspezifität: AA 140-190, N-Term

Spezifität: This antibody will only detect the NIL-16 isoform.

Aufreinigung: IL-16 Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-16 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human IL-16. The immunogen is located within amino acids 140 - 190 of IL-16.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-16 antibody can be used for detection of IL-16 by Western blot at 2.5 - 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-16 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu IL16

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: IL-16

Hintergrund: IL-16 Antibody: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus.

Molekulargewicht: Predicted: 145 kDa

Observed: 160 kDa

Gen-ID: 3603

UniProt: Q14005